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注射用血凝酶在腹腔镜胃癌根治术中止血作用的临床研究
作者:胡俊峰  孙元水 
单位:浙江省人民医院胃肠外科  浙江 杭州 310014 
关键词:胃肿瘤/外科学 巴曲酶/治疗应用 止血 手术 腹腔镜检查 胃切除术/方法 治疗结果 随机对照试验 
DOI:R735.2;R730.56
出版年,卷(期):页码:2014,29(4):378-379
摘要:
目的 探讨注射用血凝酶(巴曲亭)在腹腔镜胃癌根治术中和术后止血效果及对凝血功能的影响。方法 选取行腹腔镜手术治疗的28例胃癌患者,随机分为血凝酶组和对照组。观察两组创面止血时间、术中出血量、术后3天创面出血渗血量及对患者凝血功能的影响。结果 血凝酶组患者创面止血时间、术中出血量、术后3天创面出血及渗血量均明显少于对照组(均P<0.05);两组术前和术后凝血功能差异无统计学意义(P>0.05)。结论 血凝酶在腹腔镜胃癌手术术中及术后具有良好的止血效果,对患者凝血功能无影响,临床应用安全有效。
Objective To evaluate the efficacy and adverse effect of hemocoagulase in laparoscopic radical gastrectomy for gastric cancer.Methods Twenty-eight patients with gastric cancer undergoing laparoscopic radical gastrectomy were assigned to hemocoagulase group and control group randomly.Hemostatic time, hemorrhagic volume, total drainage volume 3 d after operation and coagulation function were measured and compared between two groups.Results Hemostatic time, hemorrhagic volume and total drainage volume 3 d after operation in hemocoagulase group were all significantly reduced compared to control group(all P<0.05).There were no significant differences in coagulation function before and after operation in two groups (P>0.05).Conclusion Hemocoagulase is effective and safe in preventing and treating bleeding during and after laparoscopic radical gastrectomy for gastric cancer.
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