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左右半结肠癌临床病理对比研究
作者:黄兴  黄忠诚 
单位:湖南省人民医院普外一科  湖南 长沙 410005 
关键词:结肠肿瘤 病理学 回顾性研究 
DOI:R735.3+5
出版年,卷(期):页码:2017,32(6):529-532
摘要:

目的 探讨左、右半结肠癌临床特征差异。方法 回顾性分析852例行标准结直肠癌根治术患者的临床资料,比较左、右半结肠癌患者的临床病理特征。结果 左、右半结肠癌患者在年龄和性别方面比较,差异均具有统计学意义(均P < 0.05),相较于左半结肠癌患者,右半结肠癌多见于女性和≥70岁患者。两组患者在病理组织类型、分级、浸润深度、有无神经和(或)脉管侵犯及淋巴结转移情况方面比较,差异均具统计学意义(均P < 0.05),而在就诊时远处转移率方面比较,差异无统计学意义(P > 0.05)。结论 与左半结肠癌比较,右半结肠癌多见于低、未分化腺癌和黏液腺癌,浸润深度较大,神经和(或)脉管侵犯和淋巴结转移较多。

Objective To compare the clinicopathological features between right-and left-sided colon cancer.Methods The clinicopathological data of 852 colorectal cancer patients receiving standard radical resection were retrospectively analyzed.The clinicopathological features were compared between patients with right-and left-sided colon cancer. Results Compared with left-sided colon cancer, right-sided colon cancer was more common in females and patients aged ≥ 70 years(both P<0.05). There were significant differences in pathological types, tumor grades, infiltration depth, nerve or vascular invasion, and lymph node metastasis between right-and left-sided colon cancer(all P<0.05). However, there was no significant difference in distant metastasis rate between two groups (P>0.05). Conclusion Compared with left-sided colon cancer, low-differentiated or undifferentiated adenocarcinoma and mucinous adenocarcinomas with deep infiltration, nerve and vascular invasion and lymph node metastasis are more common in right-sided colon cancer.

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