首页365bet娱乐官网网址365bet国际娱乐城365bet体育在线官电子期刊下载专区广告合作征稿启事留言板
位置:首页 >> 电子期刊 >> 正文
胸腺瘤合并重症肌无力患者术后预后影响因素分析
作者:苏树伟  崔海银  田辉  李林  岳韦名 
单位:山东省交通医院急诊科  山东 济南 250031 山东大学齐鲁医院胸外科  山东 济南 250012 
关键词:胸腺肿瘤/外科学 胸腺切除术/方法 重症肌无力/外科学 预后 危险因素 logistic模型 随访研究 
DOI:R736.3;R730.56
出版年,卷(期):页码:2018,33(1):70-72
摘要:

目的 探索影响胸腺瘤合并重症肌无力患者预后的危险因素。方法 纳入163例胸腺瘤合并重症肌无力患者,所有患者均行胸腺切除术,收集患者住院期间的临床资料,采用单因素与多因素Logistic回归分析,分析影响影响术后预后的危险因素。结果 单因素分析显示年龄(t=2.784,P=0.020)、Osserman分型(χ2=7.369,P=0.018)、术前病程(Z=4.550,P=0.001)和Masaoka分期(χ2=12.413,P<0.01)为影响患者的预后因素;多因素Logistic回归分析显示,Osserman分型(RR=2.675,95%CI:1.243~5.678,P=0.021)、术前病程(RR=1.173,95%CI:1.067~1.487,P=0.001)和年龄(RR=1.719,95%CI:1.164~3.082,P=0.023)为影响胸腺瘤合并重症肌无力患者术后预后的独立危险因素。结论 Osserman分型、术前病程和年龄为影响术后预后的独立危险因素。

Objective To investigate the risk factors of the postoperative prognosis in patients with thymoma complicated with myasthenia gravis.Methods One-hundred-and-sixty-three patients of thymoma complicated with myasthenia gravis were enrolled.All patients underwent thymectomy.Clinical information was collected for these patients,and risk factors influencing postoperative prognosis were examined by univariate and Logistic multivariate regression analysis.Results Univariate analysis suggested age(t=2.784,P=0.020),Osserman classification(χ2=7.369,P=0.018),preoperative course of the disease(Z=4.550,P=0.01),and Masaoka classification(χ2=12.413,P<0.01)as factors influencing the patient prognosis.Moreover,multivariate Logistic regression analysis showed that Osserman classification(RR=2.675,95%CI:1.243-5.678,P=0.021),preoperative course of the disease(RR=1.173,95%CI:1.067-1.487,P=0.001),and age (RR=1.719,95%CI:1.164-3.082,P=0.023) were independent risk factors of the postoperative prognosis in patients with thymoma and myasthenia gravis.Conclusion Osserman classification,preoperative course of the disease and age are independent risk factors of the postoperative prognosis in patients with thymoma complicated with myasthenia gravis.

文章下载】【加入收藏

浙ICP备18004413号

技术服务qq:1507079184(投稿系统问题可找我)

编辑部地址:浙江省杭州市上城区解放路88号(浙医二院内)

电话:0571-87783654 邮编:310009 E-mail:shyzhl@zju.edu.cn

期刊介绍 使用帮助 | 365bet体育在线官 | 留言板